PANTOPRAZOLE 40 MG (EC) + DOMPERIDONE 30 MG (SR)

DESCRIPTION

Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR) is a combination of Domperidone and Pantoprazole. It is utilized in the treatment of peptic ulcers (bruises in the stomach that frame due to overabundance corrosive) and gastroesophageal reflux infection (a condition where the stomach corrosive streams back into the nourishment pipe and harms it). These conditions lead to side effects such as acid reflux, distress in the stomach, heaving sensation, and trouble in gulping nourishment. antotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR) decreases the sensation of queasiness and diminishes the generation of stomach corrosive. In this way, it makes a difference to recuperate ulcers.

INDICATION

• Gastroesophagal reflux disease : Gastroesophageal Reflux Illness (GERD) is a infection that happens when stomach corrosive regularly streams back into the nourishment pipe. Acid reflux, stomach disturbed, trouble in gulping nourishment, and sickness are the primary side effects of GERD. Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR) makes a difference in the treatment of GERD by diminishing stomach corrosive generation and halting the sensation of nausea.

• Peptic Ulcer : Peptic ulcers are bruises (harmed and excruciating regions) on the lining of the nourishment pipe, stomach, and little digestive system. They happen due to overabundance corrosive generation in your stomach. Acid reflux and stomach disturbed are the fundamental side effects of peptic ulcers. Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR) makes a difference in the treatment of peptic ulcers by diminishing stomach corrosive generation

Peptic Ulcer

MECHANISM OF ACTION

Pantoprazole 40 mg (EC): Pantoprazole is a proton pump inhibitor (PPI) that works by irreversibly inhibiting the H+/K+ ATPase enzyme in the parietal cells of the stomach lining. This enzyme is responsible for the final step in the production of gastric acid. By blocking this enzyme, pantoprazole significantly reduces stomach acid secretion, alleviating symptoms associated with acid reflux and promoting healing of the stomach lining. The enteric coating ensures that pantoprazole is released in the intestine rather than the stomach, protecting the drug from being inactivated by stomach acid and allowing it to be absorbed effectively.

Domperidone 30 mg (SR): Domperidone is a dopamine D2 receptor antagonist that primarily enhances gastrointestinal motility. It works by blocking dopamine receptors in the gut, which increases the movement of the stomach and intestines, facilitating faster gastric emptying. Additionally, domperidone blocks dopamine receptors in the chemoreceptor trigger zone (CTZ) in the brain, helping to reduce nausea and vomiting. The sustained-release formulation ensures a prolonged and steady release of the drug, providing longer-lasting effects in managing symptoms.

DRUG INTERACTIONS

Drug-Drug Interactions: Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR) may interact with a blood thinner (e.g. clopidogrel, warfarin), antifungal (e.g. ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (e.g. atazanavir, nelfinavir), iron supplements, antibiotic (e.g. ampicillin, rifampicin), heart medicine (e.g. digoxin) and anti-cancer drug (e.g. methotrexate). Let your doctor know if you are taking these medicines.

Drug-Food Interactions: Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR) interacts with St John's wort plant that is used as an anti-depressant. This plant may affect the working of Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR). So avoid its intake with Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR).

Drug-Disease Interactions: Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR) should not be given in patients with C. difficile-induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), and low magnesium (hypomagnesemia).

SIDE EFFECTS PANTOTEC-DSR CAPSULE

Major & minor side effects for Pantotec-DSR Capsule

• Headache
• Altered sense of taste
• Diarrhea
• Unusual tiredness and weakness
• Skin Rash
• Difficulty in breathing
• Disrupted menstrual cycle
• Breast pain and tenderness
• Dry mouth
• Swelling of ankles or feet
• Dark urine
• Dizziness
• Stomach pain
• Visual disturbances

PRECAUTIONS

When using Pantotec-DSR Capsule (Pantoprazole 40 mg (EC) + Domperidone 30 mg (SR), caution is needed due to the risk of heart rhythm problems associated with domperidone, especially in patients with existing heart conditions. Monitor liver and kidney function, as both drugs may require dosage adjustments in cases of impairment. Long-term use of pantoprazole can lead to vitamin B12 deficiency and bone issues, so regular monitoring is recommended. Additionally, be aware of potential drug interactions, particularly with medications that affect heart rhythm or acid levels.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.