PANTOPRAZOLE 40 MG + DOMPERIDONE 10 MG

DESCRIPTION

Opet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg) is a combination of Domperidone and Pantoprazole. It is utilized in the treatment of peptic ulcers (bruises in the stomach that shape due to overabundance corrosive) and gastroesophageal reflux infection (a condition where the stomach corrosive streams back into the nourishment pipe and harms it). These conditions lead to indications such as acid reflux, inconvenience in the stomach, spewing sensation, and trouble in gulping nourishment. Opet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg)  diminishes the sensation of queasiness and diminishes the generation of stomach corrosive. In this way, it makes a difference to recuperate ulcers.

INDICATION

Gastroesophagal reflux disease : Gastroesophageal Reflux Malady (GERD) is a malady that happens when stomach corrosive regularly streams back into the nourishment pipe. Acid reflux, stomach disturbed, trouble in gulping nourishment, and queasiness are the fundamental indications of GERD. Pantomed D Tablet makes a difference in the treatment of GERD by diminishing stomach corrosive generation and halting the sensation of nausea.

Peptic Ulcer : Peptic ulcers are bruises (harmed and excruciating regions) on the lining of the nourishment pipe, stomach, and little digestive system. They happen due to abundance corrosive generation in your stomach. Acid reflux and stomach disturbed are the fundamental side effects of peptic ulcers. Pantomed D Tablet makes a difference in the treatment of peptic ulcers by diminishing stomach corrosive generation.

MECHANISM OF ACTION

Pantoprazole: As a proton pump inhibitor (PPI), pantoprazole works by irreversibly inhibiting the H+/K+ ATPase enzyme in the parietal cells of the stomach lining. This enzyme is responsible for the final step in gastric acid production. By blocking this enzyme, pantoprazole significantly reduces stomach acid secretion, helping to relieve symptoms of acid reflux and allowing healing of the stomach lining.

Domperidone: Domperidone is a dopamine D2 receptor antagonist that primarily works by enhancing gastrointestinal motility. It blocks dopamine receptors in the gut, which increases the movement of the stomach and intestines, promoting the faster passage of food through the stomach. Additionally, by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) in the brain, domperidone helps to prevent nausea and vomiting.

DRUG INTERACTIONS

Drug-Drug Interaction: Opet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg) may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Food Interaction: Opet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg) interacts with St John's wort plant that is used as an anti-depressant. This plant may affect the working ofOpet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg). So avoid its intake with Opet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg).

Drug-Disease Interaction: Opet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg) should not be given in patients with Clostridium difficile-induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), and low magnesium (hypomagnesemia).

SIDE EFFECTS OPET-D TABLET

Major & minor side effects for Opet-D Tablet

• Headache
• Altered sense of taste
• Diarrhea
• Unusual tiredness and weakness
• Skin Rash
• Difficulty in breathing
• Disrupted menstrual cycle
• Breast pain and tenderness
• Dry mouth
• Swelling of ankles or feet
• Dark urine
• Dizziness
• Stomach pain
• Visual disturbances

PRECAUTION

When taking Opet-D Tablet (Pantoprazole 40 mg + Domperidone 10 mg), caution is advised if you have liver or kidney issues, as both drugs may require dosage adjustments. Domperidone can increase the risk of heart rhythm problems, so it should be used cautiously in patients with existing heart conditions. Long-term use of pantoprazole may lead to vitamin B12 deficiency or bone fractures. Avoid using this combination with other medications that affect heart rhythm or acid levels without consulting a doctor.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.