CEFTRIAXONE 250 MG + SULBACTUM 125 MG

DESCRIPTION

Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) is a combination pharmaceutical utilized for the treatment of contaminations of the lower respiratory tract, ears, skin and skin structure, etc. caused by helpless microscopic organisms. This pharmaceutical is not suggested for utilize in patients less than 28 days of age (neonates).

INDICATION

• Bacterial infections : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) is utilized for the treatment of contaminations caused by vulnerable bacterial species that are safe to commonly-used systemic anti-microbials or Jacef SB 750 Injection alone. These contaminations may incorporate urinary tract diseases, bone and joint diseases, intra-abdominal diseases, bacterial septicemia, pelvic fiery malady, etc.

• Bacterial Meningitis : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) is utilized in the treatment of meningitis, which is an irritation of the defensive films that encompass the brain and spinal line. This contamination may be caused by Streptococcus pneumoniae or Neisseria meningitidis.

• Skin and Skin Structure Infection : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) is utilized in the treatment of contaminations of the skin and skin structures caused by helpless microscopic organisms. These contaminations may incorporate tainted wounds, folliculitis, abscesses, cellulitis, ulcers, etc.

• Acute bacterial otitis media : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) is utilized in the treatment of an intense center ear disease (otitis media) which may be caused by microbes such as Streptococcus pneumoniae, Haemophilus parainfluenzae, etc.

• Lower Respiratory Tract Infection : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) is utilized in the treatment of lower respiratory tract diseases such as pneumonia caused by helpless species of microbes.

• Surgical prophylaxis : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) is utilized earlier to a surgical strategy to anticipate post-surgical bacterial contaminations.

MECHANISM OF ACTION

Ceftriaxone : A broad-spectrum cephalosporin anti-microbial, it works by repressing bacterial cell divider blend. Ceftriaxone ties to penicillin-binding proteins (PBPs) on the bacterial cell film, interferometer with the cross-linking of peptidoglycan layers fundamental for cell divider keenness. This leads to cell divider debilitating, bacterial lysis, and death.

Sulbactam : A β-lactamase inhibitor, it works by repressing the proteins (β-lactamases) delivered by certain microscopic organisms that would something else inactivate β-lactam anti-microbials like ceftriaxone. By avoiding these chemicals from breaking down ceftriaxone, sulbactam upgrades the adequacy of the cephalosporin, permitting it to target a broader run of microscopic organisms, counting those creating β-lactamase.

DRUG INTERACTIONS

Drug-Drug Intuitive : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) may associated with immunizations (cholera antibody) estrogens (Ethinyl estradiol), penicillin anti-microbials (mezlocillin and azlocillin), aminoglycoside anti-microbials (amikacin, streptomycin, neomycin and gentamicin), immuno-suppressant(cyclosporine) and pharmaceutical utilized to treat gout (probenecid).

Drug-Food Intelligent : No intuitive found.

Drug-Disease Intuitive : Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) ought to be utilized with caution in patients with kidney issues, diabetes, seizures, liver illnesses, gastrointestinal infections, and dying clutters.

SIDE EFFECTS OF JACEF SB 375 INJECTION
Major & minor side effects for Jacef SB 375 Injection

• Diarrhea
• Nausea and Vomiting
• Itching
• Fatigue
• Chills
• Edema
• Black or hesitate stools
• Chest pain
• Fever
• Difficult or excruciating urination
• Sore throat
• Abdominal pain
• Dizziness
• Swelling of confront, lips, eyelids, tongue, hands and feet
• Acid or acrid stomach
• Change in taste
• Excessive discuss or gas in stomach

PRECAUTIONS

Inform your healthcare supplier if you have hypersensitivities to cephalosporins, penicillins, or other β-lactam anti-microbials due to potential cross-reactivity. Uncover any history of kidney or liver illness, gastrointestinal conditions, or dying clutters, as ceftriaxone can affect kidney work and worsen gastrointestinal issues. Advise your specialist of all medicines you are taking, counting over-the-counter drugs, as Jacef SB 375 Injection (Ceftriaxone 250 mg + Sulbactum 125 mg) can connected with certain drugs, expanding dying dangers. Counsel your supplier if pregnant, arranging pregnancy, or breastfeeding. Screen renal and hepatic work and dodge concurrent utilize with calcium items, particularly in youthful children, to anticipate precipitation dangers. Be mindful of and report extreme side impacts, and guarantee legitimate weakening and organization to maintain a strategic distance from complications

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.