CLARITHROMYCIN 500 MG

DESCRIPTION

Clarom Tablet is a combination of (Clarithromycin 500 mg) are macrolide antibiotics used to treat various bacterial infections by inhibiting bacterial protein synthesis, thereby halting bacterial growth. They are effective against respiratory tract infections like pneumonia and bronchitis, skin infections, sinusitis, and sexually transmitted diseases such as chlamydia. Additionally, they are used in combination therapies to eliminate Helicobacter pylori in peptic ulcer disease.

INDICATION

• Pharyngitis/Tonsilitis : Pharyngitis and tonsillitis are infections that cause swelling and soreness in the throat and tonsils. If this infection affects both the throat and the tonsils, then it would be called pharyngotonsillitis. Clarom tablet (Clarithromycin 500 mg) is used to treat pharyngitis, tonsillitis, and/or pharyngotonsillitis.

• Bronchitis : Bronchitis is the swelling and irritation of airway passages in your lungs which is characterized by cough, wheezing, shortness of breath and fever. Clarom tablet (Clarithromycin 500 mg) is used to treat bronchitis caused by bacteria.

    
• Pneumonia : Community-acquired pneumonia (CAP) refers to pneumonia (lung infection) wherein one gets infected in a community setting. It does not happen in a hospital, nursing home, or other healthcare centres. CAP can be caused by bacteria or viruses. Clarom tablet (Clarithromycin 500 mg) is used to treat CAP caused by bacteria like Mycoplasma pneumonia, Streptococcus pneumonia, Haemophilus influenzae, etc.

• Sinusitis : Sinusitis is a condition in which the cavities around your nasal passages become swollen. It is often caused by bacteria and sometimes, viruses and fungi. You may experience a stuffed nose and pain or pressure behind your eyes, nose, cheeks, or forehead. Clarom tablet (Clarithromycin 500 mg) is used to treat bacterial sinusitis and provides relief in three to eight weeks.

• Acute otitis media : Otitis media (AOM), is an infection of the middle ear (the area behind the eardrum), common in infants and young children. Clarom tablet (Clarithromycin 500 mg) is used to treat acute otitis media caused by bacteria.

• Peptic ulcer : A peptic ulcer is a sore or ulcer on the lining of your stomach or intestine. Helicobacter pylori (H. pylori) are the bacteria that cause ulcers. Clarom tablet (Clarithromycin 500 mg) is used in combination with antacids/anti-ulcerative medicines for the treatment of H. pylori infections that cause peptic ulcers.

• Skin and soft tissue infections : Skin and soft tissue infections occur when the bacteria invade the skin and its supporting structures. Clarom tablet (Clarithromycin 500 mg) is used to treat all skin infections including abscess (infected pus pocket) caused by bacteria.

 
• Mycobacterium avium complex : Mycobacterium avium complex (MAC) lung disease is an infection caused by mycobacterium avium bacteria. These bacteria enter your body during breathing or swallowing food or water and cause lung damage. It mainly affects people with weak immune systems like those who have cancer, HIV, and those who use corticosteroid medicines for a long time. Clarom tablet (Clarithromycin 500 mg) is used to treat disseminated MAC disease (infection throughout an organ or the body), which usually affects people with AIDS.

• Pertussis : Pertussis or whooping cough is a respiratory infection caused by Bordetella pertussis bacteria characterized by severe uncontrollable coughing. It can easily spread from person to person and affects people of any age. Clarom Tablet (Clarithromycin 500 mg) is used to treat pertussis.

MECHANISM OF ACTION

Clarithromycin 500 mg a macrolide antibiotic, exerts its bacteriostatic (inhibitory) action primarily by binding to the 50S ribosomal subunit of susceptible bacteria. By binding to this subunit, clarithromycin interferes with protein synthesis, thereby inhibiting bacterial growth and multiplication. This mechanism prevents the bacteria from producing essential proteins needed for their survival and replication. As a result, the bacterial infection is halted and eventually eradicated by the body's immune system. This antibiotic is effective against a wide range of bacterial infections, including respiratory tract infections, skin infections, sinusitis, and sexually transmitted diseases.

SIDE EFFECTS OF CLAROM TABLET

Major & minor side effects for Clarom Tablet

• Indigestion
• Stomach pain
• Nausea and Vomiting
• Diarrhoea
• Itching and skin rash
• Acid or sour stomach
• Headache
• Heartburn
• Dizziness
• Lower back pain

DRUG INTERACTIONS

Drug-Drug Interactions : Clarom tablet (Clarithromycin 500 mg) interacts with certain medicines used to treat migraine (ergotamine, dihydroergotamine), antihistamines (terfenadine, astemizole), medications used to treat stomach disorders (cisapride or domperidone), antipsychotic drug (pimozide), statins or medicines used to lower levels of cholesterol (lovastatin, simvastatin, lomitapide, atorvastatin), certain sedative medications (midazolam), GOUT medications (colchicine), medicines used to treat heart attack, chest pain or angina (ticagrelor or ranolazine), medicines used to treat anxiety and panic disorder (alprazolam), and medications used to treat asthma or chronic obstructive pulmonary disease (budesonide/formoterol)

Drug-Food Interactions : No relevant interactions found.

Drug-Disease Interactions : Inform your doctor if you have liver problems, renal dysfunction, heart rhythm disorder (arrhythmia) or QT prolongation, electrolyte imbalance (low potassium or magnesium level), and muscle problems (myasthenia gravis).

PRECAUTIONS

Before taking Clarom tablet (Clarithromycin 500 mg), it's crucial to inform your healthcare provider about any allergies, especially to antibiotics like azithromycin or erythromycin. Discuss any existing liver or kidney conditions, as dosage adjustments may be necessary. Individuals with heart issues should be monitored closely for QT prolongation. If you have myasthenia gravis, use Clarom tablet cautiously, as it can exacerbate symptoms. Pregnant or breastfeeding individuals should weigh the risks and benefits with their doctor, as Clarom Tablet (Clarithromycin 500 mg) can pass into breast milk. Be vigilant about potential drug interactions and report any side effects promptly to your healthcare provider for appropriate management.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.