OMEPRAZOLE 20 MG + DOMPERIDONE 10 MG

DESCRIPTION

Elton-D Capsule (Omeprazole 20 mg + Domperidone 10 mg)  is a combination medication containing Omeprazole and Domperidone, designed to treat gastroesophageal reflux disease (GERD), particularly in patients who do not respond adequately to omeprazole alone. Omeprazole reduces stomach acid production by inhibiting the proton pump in the stomach lining, while Domperidone enhances gastrointestinal motility, helping to prevent acid reflux and associated symptoms like heartburn. In addition to GERD, Elton-D Capsule (Omeprazole 20 mg + Domperidone 10 mg) may be used to manage other gastric acid-related disorders, such as peptic ulcers and chronic indigestion. 

INDICATION

• Gastroesophagal Reflux Disease : Elton-D Capsule (Omeprazole 20 mg + Domperidone 10 mg)  is used in the treatment of reflux disease, where acid from the stomach enters and irritates the food pipe (esophagus).

Gastroesophagal Reflux Disease

• Gastric Acid Related Disorders : Elton-D Capsule (Omeprazole 20 mg + Domperidone 10 mg) is used to prevent or treat disorders such as duodenal ulcers, gastric ulcers, Zollinger-Ellison syndrome, chronic gastritis, etc. associated with an excess amount of acid secretion

MECHANISM OF ACTION

Omeprazole 20 mg is a proton pump inhibitor (PPI) that works by irreversibly inhibiting the H+/K+ ATPase enzyme located on the parietal cells of the stomach lining. This enzyme is crucial for the final step of gastric acid production. By blocking this enzyme, Omeprazole significantly reduces the secretion of stomach acid, which helps to heal acid-related damage, alleviate symptoms such as heartburn, and prevent the formation of ulcers.

Domperidone 10 mg is a dopamine D2 receptor antagonist that enhances gastrointestinal motility. It works by blocking dopamine receptors in the gut, which increases the release of acetylcholine. This, in turn, improves the tone and motility of the stomach and intestines, facilitating faster gastric emptying and reducing symptoms such as nausea, vomiting, and bloating. By promoting better movement of food through the digestive tract, Domperidone helps prevent acid reflux and other related symptoms.

DRUG INTERACTIONS

Drug-Drug Interactions : Elton-D Capsule (Omeprazole 20 mg + Domperidone 10 mg) may interact with painkillers (aspirin), antibiotics (ciprofloxacin), statin (atorvastatin), anti-HIV (atazanavir), blood thinner (clopidogrel, warfarin, cilostazol), a drug used to treat hypothyroidism (levothyroxine), anti-fungal (ketoconazole, itraconazole, voriconazole), anti-cancer (erlotinib, methotrexate), anti-depressant (citalopram, escitalopram, duloxetine), anti-anxiety (alprazolam), vitamin (cyanocobalamin), anti-convulsant (phenytoin), gastroprokinetic agent (cisapride), cardiac glycoside (digoxin), immunosuppressant (tacrolimus), anti-tuberculosis (rifampicin).

Drug-Food Interactions : No interactions found/established.

Drug-Disease Interaction : Inform your doctor if you have epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, or hypomagnesemia (low levels of magnesium).

SIDE EFFECTS OF ELTON-D CAPSULE

Major & minor side effects for Elton-D Capsule

• Swelling of face, lips, eyelids, tongue, hands and feet
• Difficulty in breathing
• Disrupted menstrual cycle
• Breast pain and tenderness
• Dry mouth
• Decreased sexual urge
• Abdominal pain
• Sore throat
• Diarrhea
• Muscle pain
• Drowsiness
• Dizziness

PRECAUTIONS

When using Elton-D Capsule (Omeprazole 20 mg + Domperidone 10 mg), several precautions should be observed. Omeprazole should be used cautiously in patients with severe liver impairment, as it can accumulate and potentially lead to liver dysfunction. Long-term use may also increase the risk of bone fractures and vitamin B12 deficiency. Domperidone may cause cardiac side effects, including QT prolongation, and should be used with caution in individuals with a history of heart disease or those taking other medications that affect heart rhythm. Both medications can interact with other drugs, so it's important to inform your healthcare provider of all medications you are taking. Pregnant and breastfeeding women should consult their healthcare provider before using this combination due to potential risks to the fetus or infant.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.