ACECLOFENAC 100 MG + THIOCOLCHICOSIDE 8 MG

DESCRIPTION

Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg) is a combination medication used to relieve pain and muscle spasms. Aceclofenac, an NSAID, reduces inflammation and pain, while Thiocolchicoside, a muscle relaxant, alleviates muscle stiffness and spasms. This combination is commonly prescribed for conditions like arthritis or acute musculoskeletal pain.

INDICATION

• Relieving Pain and Inflammation: Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg) Effective in reducing pain and inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

• Treating Muscle Spasms: Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg) Helps alleviate muscle stiffness and spasms, especially in conditions like lower back pain, cervical pain, and muscle injuries.

• Postoperative Pain Management: Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg) Often used to manage pain and muscle spasms following surgery or trauma.

MECHANISM OF ACTION 

Aceclofenac: Aceclofenac works by inhibiting the enzyme cyclooxygenase (COX), which plays a key role in the synthesis of prostaglandins. Prostaglandins are chemicals in the body responsible for causing pain, inflammation, and swelling. By reducing their production, Aceclofenac alleviates pain and inflammation.

Thiocolchicoside: Thiocolchicoside  muscle relaxant works by acting on the central nervous system, specifically targeting GABA (gamma-aminobutyric acid) receptors. It inhibits muscle contractions and reduces muscle spasms by modulating the activity of neurotransmitters involved in muscle movement and tone.

DRUG INTERACTION

Drug-Drug Interaction: Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg) may have interaction with medicines used to lower high blood pressure (lisinopril, enalapril, candesartan, losartan, clonidine, moxonidine, hydralazine, methyldopa, propranolol), antibiotics (ciprofloxacin, moxifloxacin, ofloxacin, levofloxacin), water pills (furosemide, amiloride), blood thinners (heparin, warfarin, clopidogrel), anticancer drug (methotrexate), HIV drug (zidovudine), antidiabetic drugs (gliclazide, tolbutamide, glibenclamide), pain killers (ibuprofen, naproxen, aspirin, celecoxib, etoricoxib), steroids (hydrocortisone, prednisolone), medicines used for abortion (mifepristone), immunosuppressants (ciclosporin, tacrolimus), antimanic drug (lithium), heart-related medicines (digoxin), and antidepressants (fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram).

Drug- Food Interaction: Avoid the intake of alcohol with Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg as it may increase the risk of severe adverse effects.

Drug-Disease Interaction: If you have asthma, diabetes, high blood pressure, stomach ulcer, high cholesterol, chickenpox, porphyria (rare inherited disorder), systemic lupus erythematosus (an autoimmune disease), ulcerative colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss), galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), fits, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), bleeding or blood clotting disorders, kidney, liver or heart diseases, inform your doctor before taking Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg.

SIDE EFFECTS OF PESAK-TH TABLET

Major & minor side effects for Pesak-TH Tablet

• Itching and skin rash
• Swelling of face, lips, eyelids, tongue, hands and feet
• Nausea and Vomiting
• Diarrhoea
• Yellowing of skin and eyes
• Dry mouth
• Headache
• Stomach pain
• Heartburn
• Loss of appetite
• Dizziness

PRECAUTIONS

When using Pesak-TH Tablet (Aceclofenac 100 mg + Thiocolchicoside 8 mg), take precautions to avoid gastrointestinal issues such as ulcers or bleeding by using the medication with food. Monitor for signs of liver or kidney dysfunction, as Aceclofenac can impact these organs. Be cautious of drowsiness or dizziness caused by Thiocolchicoside, which may impair your ability to drive. Consult your healthcare provider before use if you have a history of cardiovascular disease or are taking other medications.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.