ACECLOFENAC 100 MG + PARACETAMOL 325 MG + CHLORZOXAZONE 250 MG

DESCRIPTION

Pesak-MR is a medication that contains 100 mg of Aceclofenac Sodium, 325 mg of Paracetamol, and 250 mg of Chlorzoxazone to reduce pain, inflammation, and muscle spasms. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces heat, inflammation, and pain by inhibiting certain enzymes (COX enzymes) that generate prostaglandins, which cause pain and swelling. Acetaminophen, sometimes referred to as paracetamol, reduces fever by stopping the brain from creating pain-producing chemicals. The muscle relaxant chlorzoxazone helps lessen muscle stiffness and spasms by relaxing the muscles and lowering associated pain. Arlac-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) is a common treatment for musculoskeletal, joint, back, and arthritic pain. It relaxes muscles and relieves pain.

INDICATION

1. Musculoskeletal Pain: Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) is successfully relieved the pain from sprains, strains, and other muscle injuries. Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) improves mobility and speeds up recovery by reducing pain and inflammation.
   
    
2. Arthritis: In patients with osteoarthritis and rheumatoid arthritis, Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) helps control joint pain, minimize swelling, and relieve muscular stiffness. Overall function is enhanced with Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg).
   
    
3. Back Pain: For both acute and chronic lower back pain, Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) provides all-encompassing relief, especially in cases of muscular spasms. This helps with conditions like sciatica or lumbar strain by reducing inflammation, easing tense muscles, and relieving pain.
   
    
4. Postoperative Pain: When muscular spasms occur during the healing process after surgery, Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) combination can help control pain and discomfort. By reducing inflammation and muscular tension, Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) facilitates a speedier recovery.
   
    
5. Acute Injuries: Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) assists with acute injuries such as ligament sprains, fractures, or soft tissue injury by reducing pain, controlling swelling, and relaxing muscles. Pesak-MR (100 mg of Aceclofenac Sodium + 325 mg of Paracetamol + 250 mg of Chlorzoxazone) encourages greater mobility and faster recovery.
   
    

MECHANISM OF ACTION 

• Paracetamol (325 mg): The main way that paracetamol affects the central nervous system is by inhibiting a variant of the brain COX enzyme (COX-3).  Without significantly reducing inflammation, this decreases temperature and reduces pain by reducing the manufacture of pain-causing chemicals. It works well with other medications and effectively reduces mild to moderate pain.
  
   
• Chlorzoxazone (250 mg): During spasms, this muscle relaxant stops muscles from contracting. It reduces muscle tone, relaxes stiffness, and lessens spasms by acting on the central nervous system. This aids in muscular relaxation and reduces discomfort associated with tense or spasmatic muscles.
  
   
• Aceclofenac (100 mg): As a nonsteroidal anti-inflammatory drug (NSAID), aceclofenac works by inhibiting the cyclooxygenase (COX) enzyme, which is responsible for producing prostaglandins, which are chemicals that induce inflammation, fever, and discomfort. By blocking COX, aceclofenac reduces pain, swelling, and inflammation in conditions like arthritis and muscle injuries.
  
  
  
   

SIDE EFFECTS OF PESAK-MR TABLET

Major & minor side effects for Pesak-MR Tablet

• Nausea
• Vomiting
• Heartburn
• Stomach pain
• Diarrhoea
• Loss of appetite
• Tiredness
• Sleepiness

DRUG INTERACTIONS
 

Drug-Drug Interactions : Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) tablet interacts with an antidepressant (duloxetine), an antiallergic (diphenhydramine, cetirizine), a muscle relaxant, an antispasmodic (baclofen), antiepileptics or medications for fits (gabapentin, topiramate, pregabalin), painkillers (tramadol, oxycodone, hydrocodone), a diuretic, or water pills (fluoxetine).

Drug-Food Interactions : The use of St. John's wort, a herbal supplement used as an antidepressant, with Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) tablets should be avoided because it can interact with the medication and cause dizziness.

Drug-Disease Interactions: Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) should not be used by those who have liver illness, renal disease, alcoholism, stomach ulcers, or bleeding intestinal ulcers.

PRECAUTIONS
 

Since both aceclofenac and paracetamol can impair liver function, especially when taken for an extended period of time, people with liver or renal problems should use Pesak-MR, which is a combination of Aceclofenac 100 mg, Paracetamol 325 mg, and Chlorzoxazone 250 mg, with caution. Because NSAIDs like aceclofenac might irritate the stomach lining and raise the risk of bleeding, anyone with a history of gastrointestinal ulcers or bleeding problems should not take it. Patients who are older may be more vulnerable to adverse effects such renal issues and gastrointestinal distress. Due to possible dangers to the baby, pregnant women, particularly those in the third trimester, and nursing mothers should refrain from taking Pesak-MR (Aceclofenac Sodium 100 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) unless directed by a physician.

 DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.