Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg

DESCRIPTION

SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg) Tablets combine two effective antidiabetic medicines with complementary mechanisms of action. Sitagliptin enhances the body's natural incretin hormones, promoting insulin release and reducing glucose production by the liver after meals. Dapagliflozin works by inhibiting SGLT2 in the kidneys, allowing excess glucose to be excreted in the urine. SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg ), they provide effective and sustained glycemic control, helping reduce HbA1c levels while supporting weight management and offering cardiovascular 

INDICATION

• BLOOD SUGER  CONTROL .  SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg ) Helps improve glycemic (blood sugar) control along with a healthy diet and regular exercise. 

• BLOOD SUGER  . SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg )Suitable for patients whose blood sugar is not adequately controlled with a single antidiabetic medicine. 

• POSTPRANDIAL BLOOD GLUCOSE . SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg ) Helps reduce fasting blood glucose (FBG) and postprandial blood glucose (PPBG). 

• HbA1c LEVELS . SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg ) Aids in lowering HbA1c levels. 

• BENEFICIAL FOR OVERWEIGHT .  SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg ) Beneficial for overweight or obese patients, as it may support modest weight reduction. 

MECHANISM OF ACTION

Sitagliptin Phosphate (DPP-4 Inhibitor):

• Inhibits the Dipeptidyl Peptidase-4 (DPP-4) enzyme.
• Increases the levels of incretin hormones (GLP-1 and GIP).
• Enhances glucose-dependent insulin secretion from pancreatic β-cells.
• Reduces glucagon secretion from pancreatic α-cells.
• Decreases hepatic glucose production, helping to lower blood glucose levels.

Dapagliflozin Propanediol (SGLT2 Inhibitor):

• Selectively inhibits the Sodium-Glucose Co-Transporter 2 (SGLT2) in the proximal renal tubules.
• Reduces renal glucose reabsorption.
• Increases urinary glucose excretion, thereby lowering plasma glucose levels.
• Provides an insulin-independent mechanism for reducing blood glucose levels and may contribute to modest weight and blood pressure reduction.

DRUG INTERACTIONS

Drug-Drug Interaction : SITAVAC-D 100/10 (Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg) Tablets may interact with insulin and insulin secretagogues, which may increase the risk of hypoglycemia. Diuretics may increase the risk of dehydration and low blood pressure. Inform your healthcare professional about all medicines being taken.

Drug-Food Interaction : No specific clinically significant food interaction has been established with SITAVAC-D 100/10 Tablets. The tablets should be taken as directed by the healthcare professional.

Drug-Disease Interaction : Inform your healthcare professional if you have kidney disease, a history of pancreatitis, dehydration, or recurrent urinary or genital infections before taking SITAVAC-D 100/10 Tablets.

SIDE EFFECTS OF SITAVAC-D 100/10 TABLET

Major & minor side effects for SITAVAC-D 100/10 Tablet

• Headache
• Nausea
• Cough
• Dizziness

PRECAUTION

Sitagliptin Phosphate 100 mg + Dapagliflozin Propanediol 10 mg Tablets should be used as directed by a healthcare professional. Monitor kidney function and blood glucose regularly. Maintain adequate hydration and watch for urinary or genital infections. Inform your healthcare professional about any kidney problems, pancreatitis, or other medical conditions. Use during pregnancy or breastfeeding only as advised by a healthcare professional.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.