NITROFURANTOIN 100 MG

DESCRIPTION

Furatec Tablet (Nitrofurantoin 100 mg) belongs to a group of antibacterial or antibiotics. Furatec Tablet is used to prevent and treat bacterial infections like urinary tract infections (UTIs), including Bladder Infection (cystitis). Besides this, it is also used in to treat kidney infections. A urine infection is often called a urinary tract infection (or simply, UTI). Most urine infections are caused by germs (bacteria). 

INDICATION

• Treatment of UTIs: Furatec Tablet (Nitrofurantoin 100 mg) is used to treat acute uncomplicated urinary tract infections caused by susceptible bacteria, such as E. coli and Enterococcus species.

• Prevention of recurrent UTIs: Furatec Tablet (Nitrofurantoin 100 mg) is prescribed for long-term prevention of recurring UTIs in individuals who are prone to frequent infections.
   

• Cystitis: Furatec Tablet (Nitrofurantoin 100 mg) is often used specifically for the treatment of cystitis (bladder infection), a common form of UTI.
   

• Selective antibiotic: Furatec Tablet (Nitrofurantoin 100 mg) is particularly useful in targeting bacteria in the urinary tract since it concentrates in the urine.
   

MECHANISM OF ACTION

Nitrofurantoin 100 mg works by inhibiting bacterial enzymes, which convert it into highly reactive intermediates inside the bacterial cells. These intermediates attack and damage critical components of the bacteria, including DNA, RNA, proteins, and cell walls, leading to bacterial cell death. Nitrofurantoin is particularly effective in the urinary tract, as it is rapidly excreted into the urine, allowing it to concentrate at the site of infection. Its action is bactericidal at therapeutic doses, meaning it kills the bacteria rather than just inhibiting their growth. This mechanism makes it especially useful for treating urinary tract infections.

DRUG INTERACTIONS

Drug-Drug interactions: Furatec Tablet (Nitrofurantoin 100 mg)  may have an interaction with Vaccines [such as Bacillus Calmette-Guerin (BCG),  cholera vaccine, live, typhoid vaccine, live], a medicine used to treat relapsing forms of multiple sclerosis (teriflunomide), medications to treat rheumatoid arthritis (leflunomide), cholesterol-lowering medications (lomitapide), cholesterol-lowering pills (mipomersen), medication is used to treat a certain type of tumour (pexidartinib), a topical anaesthetic (prilocaine), and medicine used to treat relapsing forms of multiple sclerosis (teriflunomide).

Drug-Food Interactions:  Furatec Tablet (Nitrofurantoin 100 mg)  interacts with grapefruit, foods rich in calcium, and a large volume of alcohol. Grapefruit contains compounds known as furanocoumarins, which interfere with how the liver and intestines break down the medicine and filter out toxins.

Drug-Disease Interactions: Inform your doctor if you have or have ever had colitis (a chronic digestive disease characterized by inflammation of the inner lining of the colon), G-6-PD deficiency (hemolytic anaemia), hepatotoxicity (Liver Disease), Renal Dysfunction (kidney disease), peripheral neuropathy (weakness, numbness and pain from nerve damage), and respiratory disorders.

SIDE EFFECTS OF FURATEC TABLET

Major & minor side effects for Furatec Tablet

• Feeling sick (nausea)
• Dizziness or feeling sleepy
• Being sick (vomiting)
• Loss of appetite
• Diarrhoea
• Headaches

PRECAUTIONS

When taking Furatec Tablet (Nitrofurantoin 100 mg), several precautions are important to ensure safe use. Individuals with severe kidney impairment should avoid this medication, as reduced kidney function can affect its effectiveness and clearance. It should also be avoided by those allergic to nitrofurantoin, as it may trigger severe allergic reactions. Long-term use can lead to lung or liver toxicity, so any signs of breathing difficulties, cough, or jaundice should be reported to a doctor immediately. Pregnant women should avoid nitrofurantoin in the last trimester due to the risk of hemolytic anemia in the newborn. Those with conditions like diabetes or vitamin B deficiency should be cautious, as there is a risk of peripheral neuropathy. Taking the medication with food helps reduce the likelihood of stomach upset, and it's normal for urine to become brownish during use. Lastly, it’s essential to inform your healthcare provider about other medications, as nitrofurantoin can interact with certain drugs, such as magnesium-containing antacids. Long-term use should be closely monitored to avoid complications.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.